Homicide detectives are investigating the death of a man who was found seriously injured on a street corner in Perth.

Police were called to the corner of Great Northern Highway and Margaret Street in Midland about 5pm yesterday.

A man aged in his 30s was found seriously injured and taken to hospital, where he later died.

The homicide squad are investigating and questioning three people in relation to the death. 

Detectives are urging anyone with information or vision to contact Crime Stoppers.

DOWNLOAD THE 9NEWS APP: Stay across all the latest in breaking news, sport, politics and the weather via our news app and get notifications sent straight to your smartphone. Available on the Apple App Store and Google Play.